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Negative side effects that might occur include peelings, mild inflammation blemished skin, burning, heat, stinging, itching, tingling, dryness, soreness, or swelling.

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Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with such as those used for their anorectic effects.

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In addition, using real time PCR, we measured mRNA levels of the cytokines interleukin-2 (IL-2), IL-18, and interferon (IFN)-gamma taken from selected punch biopsy specimens before and during treatment.

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