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Reference to a continuous or continual release is intended to encompass release that occurs as the result of biodegradation in vivo of the drug depot, or a matrix or component thereof, or as the result of metabolic transformation or dissolution of the therapeutic agent(s) or conjugates of therapeutic agent(s).
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Per ciascun paziente deve essere ricercata la dose più bassa ma utile a determinare una risposta terapeutica ottimale.
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It has all been reported to the drugs regulation authority in the uk and two drug companies are involved at the moment in investigating the whole process and my long term prognosis.
When used in the management of spasticity, treatment with BoNT-A is almost never used as monotherapy.
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